Ludwig Simon was born in 1997. The son of actors Maria Simon and Devid Striesow played his first major TV role in an episode of the TV show "Flemming" (2011). He appeared alongside his father in "Göttliche Funken" (2014), and together with his mother in the "Polizeiruf 110" episode "Hexenjagd".

In 2017, Ludwig Simon played the son of police detective Jens Stellbrink (played by Devid Striesow) in the "Tatort" entry "Söhne und Väter". The same year, he guest-starred in episodes of "Die Eifelpraxis", "Bettys Diagnose" and "Letzte Spur Berlin". Following his roles in Sherry Hormann's tragicomedy "Wir lieben das Leben" (2018, TV) and Mark Monheim's drama "Alles Isy" (2018, TV), Ludwig Simon got his first major part in a theatrical release as the male lead in Marco Petry's teen comedy "Meine teuflisch gute Freundin" (2018).