In 1864, American soldiers massacre a Cheyenne village at Sand Creek. Disgusted by the massacre, Harmonika, one of the soldiers, deserts the army and is captured by the Indians. At first, the Cheyenne hold him responsible for the murder of the wife and the son of their chief Grauer Esel, but soon Harmonika obtains the tribe′s confidence. Thus, Harmonika learns about the lies of the white men about the allegedly wild Indians and becomes friends with his former adversary, Harter Felsen. Later, Harmonika even marries Rehkitz, Harter Felsen′s sister. But when the tribe is attacked once more, Rehkitz is murdered by the white men. Although Harmonika gets hold of her murderer, he is not able to take bloody revenge. Disillusioned and broken, Harmonika abandons himself to alcohol. But when Harter Felsen is captured, Harmonika finally comes to his senses. He rescues his friend, whereupon Harter Felsen and Harmonika become blood brothers. Together, they continue to fight for the oppressed Cheyenne.
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